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Article

Family-based bivariate association tests for quantitative traits.

PloS one - 2 Dec 2009

Zhang Lei, Bonham Aaron J, Li Jian, Pei Yu-Fang, Chen Jie, Papasian Christopher J, Deng Hong-Wen

Abstract excerpt

The availability of a large number of dense SNPs, high-throughput genotyping and computation methods promotes the application of family-based association tests. While most of the current family-based analyses focus only on individual traits, joint analyses of correlated traits can extract more information and potentially improve the statistical power. However, current TDT-based methods are low-powered. Here, we...

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PMID: 19956578
DOI: 10.1371/journal.pone.0008133
PMCID: PMC2779861

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