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Article

Approximate conditional phenotype analysis based on genome wide association summary statistics.

Scientific reports - 28 Jan 2021

Wu Peitao, Wang Biqi, Lubitz Steven A, Benjamin Emelia J, Meigs James B, Dupuis Josée

Abstract excerpt

Because single genetic variants may have pleiotropic effects, one trait can be a confounder in a genome-wide association study (GWAS) that aims to identify loci associated with another trait. A typical approach to address this issue is to perform an additional analysis adjusting for the confounder. However, obtaining conditional results can be time-consuming. We propose an approximate conditional phenotype...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 33510268
DOI: 10.1038/s41598-021-82000-1
PMCID: PMC7843738

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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