Article
GWAB: a web server for the network-based boosting of human genome-wide association data.
Nucleic acids research - 3 Jul 2017
Shim Jung Eun, Bang Changbae, Yang Sunmo, Lee Tak, Hwang Sohyun, Kim Chan Yeong, Singh-Blom U Martin, Marcotte Edward M, Lee Insuk
Abstract excerpt
During the last decade, genome-wide association studies (GWAS) have represented a major approach to dissect complex human genetic diseases. Due in part to limited statistical power, most studies identify only small numbers of candidate genes that pass the conventional significance thresholds (e.g. P ≤ 5 × 10-8). This limitation can be partly overcome by increasing the sample size, but this comes at a higher cost....
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.