Article
A knowledge-based weighting framework to boost the power of genome-wide association studies.
PloS one - 31 Dec 2010
Li Miao-Xin, Sham Pak C, Cherny Stacey S, Song You-Qiang
Abstract excerpt
BACKGROUND: We are moving to second-wave analysis of genome-wide association studies (GWAS), characterized by comprehensive bioinformatical and statistical evaluation of genetic associations. Existing biological knowledge is very valuable for GWAS, which may help improve their detection power par...
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