araGWAB: Network-based boosting of genome-wide association studies in Arabidopsis thaliana.

Abstract excerpt

Genome-wide association studies (GWAS) have been applied for the genetic dissection of complex phenotypes in Arabidopsis thaliana. However, the significantly associated single-nucleotide polymorphisms (SNPs) could not explain all the phenotypic variations. A major reason for missing true phenotype-associated loci is the strict P-value threshold after adjustment for multiple hypothesis tests to reduce false...

Topics

• Arabidopsis
• Gene Regulatory Networks
• Genome-Wide Association Study
• Internet
• Phenotype
• Polymorphism, Single Nucleotide