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Article

Recent advances in network-based methods for disease gene prediction.

Briefings in bioinformatics - 20 Jul 2021

Ata Sezin Kircali, Wu Min, Fang Yuan, Ou-Yang Le, Kwoh Chee Keong, Li Xiao-Li

Abstract excerpt

Disease-gene association through genome-wide association study (GWAS) is an arduous task for researchers. Investigating single nucleotide polymorphisms that correlate with specific diseases needs statistical analysis of associations. Considering the huge number of possible mutations, in addition to its high cost, another important drawback of GWAS analysis is the large number of false positives. Thus, researchers...

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PMID: 33276376
DOI: 10.1093/bib/bbaa303

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