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Article

KLRG1 impairs regulatory T-cell competitive fitness in the gut.

Immunology - 1 Sept 2017

Meinicke Holger, Bremser Anna, Brack Maria, Schrenk Klaudia, Pircher Hanspeter, Izcue Ana

Abstract excerpt

Immune homeostasis requires the tight, tissue-specific control of the different CD4+ Foxp3+ regulatory T (Treg) cell populations. The cadherin-binding inhibitory receptor killer cell lectin-like receptor G1 (KLRG1) is expressed by a subpopulation of Treg cells with GATA3+ effector phenotype. Although such Treg cells are important for the immune balance, especially in the gut, the role of KLRG1 in Treg cells has...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 28437578
DOI: 10.1111/imm.12749
PMCID: PMC5543461

Genes

KLRG1
GATA3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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