Article
KLRG1 binds cadherins and preferentially associates with SHIP-1.
International immunology - 1 Apr 2007
Tessmer Marlowe S, Fugere Céline, Stevenaert Frederik, Naidenko Olga V, Chong H Jonathan, Leclercq Georges, Brossay Laurent
Abstract excerpt
The killer cell lectin-like receptor G1 (KLRG1) is a unique inhibitory receptor expressed on a phenotypically mature subset of resting NK cells as well as subsets of T cells in naive mice. In vivo, pathogenic immune system activation induces dramatic changes in the expression patterns of KLRG1 among the different cell subsets. In order to enhance our understanding of KLRG1 signaling properties and to clarify the...
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