Article
CD4+VEGFR1(HIGH) T cell as a novel Treg subset regulates inflammatory bowel disease in lymphopenic mice.
Cellular & molecular immunology - 1 Sept 2015
Shin Jin-Young, Yoon Il-Hee, Lim Jong-Hyung, Shin Jun-Seop, Nam Hye-Young, Kim Yong-Hee, Cho Hyoung-Soo, Hong So-Hee, Kim Jung-Sik, Lee Won-Woo, Park Chung-Gyu
Abstract excerpt
Regulatory T cells (Tregs) are a specialized subpopulation of T cells that control the immune response and thereby maintain immune system homeostasis and tolerance to self-antigens. Many subsets of CD4(+) Tregs have been identified, including Foxp3(+), Tr1, Th3, and Foxp3neg iT(R)35 cells. In this study, we identified a new subset of CD4(+)VEGFR1(high) Tregs that have immunosuppressive capacity. CD4(+)VEGFR1high...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
