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Article

Spatial and temporal expression patterns of genes around nine neuroticism-associated loci.

Progress in neuro-psychopharmacology & biological psychiatry - 3 Jul 2017

Ohi Kazutaka, Shimada Takamitsu, Yasuyama Toshiki, Kimura Kohei, Uehara Takashi, Kawasaki Yasuhiro

Abstract excerpt

Neuroticism is a high-order personality trait. Individuals with higher neuroticism have increased risks of various psychiatric disorders and physical health outcomes. Neuroticism is related to physiological differences in the brain. A recent genome-wide association study identified nine distinct genomic loci that contribute to neuroticism. Brain development and function depend on the precise regulation of gene...

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Source

Identifiers

PMID: 28433457
DOI: 10.1016/j.pnpbp.2017.04.019

Genes

CELF4
CRHR1
ELAVL2
GRIK3
KLHL2
PTPRD
MFHAS1
SRP9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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