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Article

Integrative analysis of genome-wide association study and common meQTLs for exploring the effects of DNA methylation on the development of neuroticism.

Journal of affective disorders - 1 Sept 2020

Zhao Shuang, Liu Zhi-Gang

Abstract excerpt

BACKGROUND: Neuroticism is one of the important traits of personality, which has strong genetic components. However, the underlying genetic mechanism is still unclear. METHODS: To better understand the genetic basis of neuroticism, we conducted an integrative analysis of genome-wide association studies (GWAS) and life course consistent methylation quantitative trait loci (meQTLs) data. The GWAS data of...

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PMID: 32469807
DOI: 10.1016/j.jad.2020.05.013

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