Article
Integrating genome-wide association study and expression quantitative trait loci data identifies multiple genes and gene set associated with neuroticism.
Progress in neuro-psychopharmacology & biological psychiatry - 1 Aug 2017
Fan Qianrui, Wang Wenyu, Hao Jingcan, He Awen, Wen Yan, Guo Xiong, Wu Cuiyan, Ning Yujie, Wang Xi, Wang Sen, Zhang Feng
Abstract excerpt
Neuroticism is a fundamental personality trait with significant genetic determinant. To identify novel susceptibility genes for neuroticism, we conducted an integrative analysis of genomic and transcriptomic data of genome wide association study (GWAS) and expression quantitative trait locus (eQTL) study. GWAS summary data was driven from published studies of neuroticism, totally involving 170,906 subjects. eQTL...
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