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Article

BRAF V600 mutation detection in melanoma: a comparison of two laboratory testing methods.

Journal of clinical pathology - 1 Nov 2017

O'Brien Odharnaith, Lyons Tomas, Murphy Sandra, Feeley Linda, Power Derek, Heffron Cynthia C B B

Abstract excerpt

AIMS: The assessment of B-raf proto-oncogene, serine/threonine kinase (BRAF) gene status is now standard practice in patients diagnosed with metastatic melanoma with its presence predicting a clinical response to treatment with BRAF inhibitors. The gold standard in determining BRAF status is currently by DNA-based methods. More recently, a BRAF V600E antibody has been developed. We aim to investigate whether...

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Identifiers

PMID: 28424234
DOI: 10.1136/jclinpath-2017-204367

Genes

BRAF

Variants

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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