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Article

BRAF V600E mutation-specific antibody: A review.

Seminars in diagnostic pathology - 1 Sept 2015

Ritterhouse Lauren L, Barletta Justine A

Abstract excerpt

The significance of BRAF mutations in neoplasia was first recognized in 2002 when mutations were discovered in a broad range of cancers. Numerous subsequent studies expanded our understanding of BRAF V600E as a critical diagnostic, prognostic, and predictive biomarker in many cancers. Additionally, the advent of small-molecule inhibitors of BRAF V600E rendered assessment of BRAF mutation status essential in...

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Identifiers

PMID: 25744437
DOI: 10.1053/j.semdp.2015.02.010

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BRAF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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