Article
BRAF V600E Mutation in Malignant Melanoma-A Romanian Research Experience.
Medicina (Kaunas, Lithuania) - 20 Feb 2024
Avădănei Elena-Roxana, Căruntu Irina-Draga, Nucă Irina, Balan Raluca, Lozneanu Ludmila, Giusca Simona-Eliza, Amalinei Cornelia
Abstract excerpt
Background and Objectives: The most common mutation in malignant melanoma (MM) is the single-point mutation of v-raf murine sarcoma viral oncogene homolog B1 (BRAF) oncogene. Our study aims to evaluate BRAF V600E mutation, highlighting its frequency differences in primary versus metastatic MM. Materials and Methods: The study group comprised 133 patients diagnosed with MM in several county hospitals of the...
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