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Article

A comparison of immunohistochemical and molecular methods used for analyzing the BRAF V600E gene mutation in malignant melanoma in Taiwan.

Asia-Pacific journal of clinical oncology - 1 Dec 2016

Huang Wen-Kuan, Kuo Tseng-Tong, Wu Chiao-En, Cheng Hsin-Yi, Hsieh Chia-Hsun, Hsieh Jia-Juan, Shen Yung-Chi, Hou Ming-Mo, Hsu Todd, Chang John Wen-Cheng

Abstract excerpt

AIMS: The BRAF V600 mutation has been shown to be clinically meaningful in terms of both the prognosis and sensitivity of BRAF inhibitors in patients with metastatic melanoma. Recently, a BRAF V600E mutation-specific antibody, VE1, was generated for the detection of tumors bearing BRAF V600E mutations. To determine the clinical value of immunohistochemical testing, we compared the prevalence of mutant BRAF...

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Identifiers

PMID: 27488807
DOI: 10.1111/ajco.12574

Genes

BRAF

Variants

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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