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Article

Multiple-gene panel analysis in a case series of 255 women with hereditary breast and ovarian cancer.

Oncotarget - 18 Jul 2017

Tedaldi Gianluca, Tebaldi Michela, Zampiga Valentina, Danesi Rita, Arcangeli Valentina, Ravegnani Mila, Cangini Ilaria, Pirini Francesca, Petracci Elisabetta, Rocca Andrea, Falcini Fabio, Amadori Dino, Calistri Daniele

Abstract excerpt

As new genes predisposing to breast (BC) and ovarian cancer (OC) are constantly emerging, the use of panels of genes analyzed by Next-Generation Sequencing (NGS) is increasing in clinical diagnostics. The identification of a large number of new germline mutations allows for deeper knowledge of cancer predisposition, although raising many questions about patient management.BC and OC patients recruited by our...

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Source

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Identifiers

PMID: 28423363
DOI: 10.18632/oncotarget.16791
PMCID: PMC5564544

Genes

BRCA1
ATM
BRCA2
BRIP1
ERCC3
MSH6
PALB2
RECQL4
SLX4
TSC2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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