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Impact of non-BRCA genes in the indication of risk-reducing surgery in hereditary breast and ovarian cancer syndrome (HBOC).

Current problems in cancer - 1 Dec 2023

Fernández Madrigal Laura, Rodríguez Garcés Maria Yeray, Jiménez Ruiz Francisco Javier

Abstract excerpt

Hereditary breast and ovarian cancer syndrome (HBOC) is associated with other genes beyond BRCA. The performance of prophylactic bilateral mastectomy (PBM) and risk-reducing salpingo-oophorectomy (RRSO) are primary prevention measures that can be recommended depending on the type of pathogenic/likely pathogenic (P/LP) variant detected or family history. Descriptive, retrospective, and observational audit. Between...

Topics

Female
Humans
Male
Genetic Predisposition to Disease
Hereditary Breast and Ovarian Cancer Syndrome
Mastectomy
Mutation
Retrospective Studies

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 37704491
DOI: 10.1016/j.currproblcancer.2023.101008

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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