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Article

Breast cancer genes: beyond BRCA1 and BRCA2.

Frontiers in bioscience (Landmark edition) - 1 Jun 2013

Filippini Sandra E, Vega Ana

Abstract excerpt

Breast cancer (BC) is a heterogeneous disease. The majority of breast cancer cases (about 70 percent) are considered sporadic. Familial breast cancer (about 30 percent of patients), often seen in families with a high incidence of BC, has been associated with a number of high-, moderate-, and low-penetrance susceptibility genes. Family linkage studies have identified high-penetrance genes, BRCA1, BRCA2, PTEN and...

Topics

Alleles
Breast Neoplasms
Female
Genes, BRCA1
Genes, BRCA2
Genetic Predisposition to Disease
Humans
Multigene Family

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 23747889
DOI: 10.2741/4185

Genes

BRCA1
BRCA2
ATM
BRIP1
CHEK2
PALB2
PTEN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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