Article
Hereditary predisposition to ovarian cancer, looking beyond BRCA1/BRCA2.
Gynecologic oncology - 1 Apr 2015
Minion Lindsey E, Dolinsky Jill S, Chase Dana M, Dunlop Charles L, Chao Elizabeth C, Monk Bradley J
Abstract excerpt
OBJECTIVE: Genetic predisposition to ovarian cancer is well documented. With the advent of next generation sequencing, hereditary panel testing provides an efficient method for evaluating multiple genes simultaneously. Therefore, we sought to investigate the contribution of 19 genes identified in the literature as increasing the risk of hereditary breast and ovarian cancer (HBOC) in a BRCA1 and BRCA2 negative...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
