Article
Gene Panel Testing in Hereditary Breast Cancer.
Archives of Iranian medicine - 1 Mar 2020
Rostami Parvin, Zendehdel Kazem, Shirkoohi Reza, Ebrahimi Elmira, Ataei Mitra, Imanian Hashem, Najmabadi Hossein, Akbari Mohammad Reza, Sanati Mohammad Hossein
Abstract excerpt
BACKGROUND: Breast cancer (BC) is a highly complex, heterogeneous and multifactorial disease and is the most commonly diagnosed cancer and the leading cause of cancer-related mortality in women worldwide. Family history and genetic mutations are important risk factors for BC. While studies in twins have estimated that about 10%-30% of BC are due to hereditary factors, only 4%-5% of them are due to mutations in...
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