Article
Survival differences of CIMP subtypes integrated with CNA information in human breast cancer.
Oncotarget - 25 Jul 2017
Wang Huihan, Yan Weili, Zhang Shumei, Gu Yue, Wang Yihan, Wei Yanjun, Liu Hongbo, Wang Fang, Wu Qiong, Zhang Yan
Abstract excerpt
CpG island methylator phenotype of breast cancer is associated with widespread aberrant methylation at specified CpG islands and distinct patient outcomes. However, the influence of copy number contributing to the prognosis of tumors with different CpG island methylator phenotypes is still unclear. We analyzed both genetic (copy number) and epigenetic alterations in 765 breast cancers from The Cancer Genome Atlas...
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