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Association Analysis of Somatic Copy Number Alteration Burden With Breast Cancer Survival

1 Oct 2018

Abstract excerpt

The increasing prevalence of diagnosed breast cancer cases emphasizes the urgent demand for developing new prognostic breast cancer biomarkers. Copy number alteration (CNA) burden measured as the percentage of the genome affected by CNAs has emerged as a potential candidate to this aim. Using somatic CNA data obtained from METABRIC (Molecular Taxonomy of Breast Cancer International Consortium), we implemented...

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PMID: 30337938
DOI: 10.3389/fgene.2018.00421

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