Article
Regulation of mitochondria-dynactin interaction and mitochondrial retrograde transport in axons.
eLife - 17 Apr 2017
Drerup Catherine M, Herbert Amy L, Monk Kelly R, Nechiporuk Alex V
Abstract excerpt
Mitochondrial transport in axons is critical for neural circuit health and function. While several proteins have been found that modulate bidirectional mitochondrial motility, factors that regulate unidirectional mitochondrial transport have been harder to identify. In a genetic screen, we found a zebrafish strain in which mitochondria fail to attach to the dynein retrograde motor. This strain carries a...
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