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Article

Evidence that myosin activity opposes microtubule-based axonal transport of mitochondria.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 30 Jun 2010

Pathak Divya, Sepp Katharine J, Hollenbeck Peter J

Abstract excerpt

Neurons transport and position mitochondria using a combination of saltatory, bidirectional movements and stationary docking. Axonal mitochondria move along microtubules (MTs) using kinesin and dynein motors, but actin and myosin also play a poorly defined role in their traffic. To ascertain this role, we have used RNA interference (RNAi) to deplete specific myosin motors in cultured Drosophila neurons and...

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Identifiers

PMID: 20592219
DOI: 10.1523/JNEUROSCI.1621-10.2010
PMCID: PMC2904968

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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