Article
Increased risk of rheumatoid arthritis among mothers with children who carry DRB1 risk-associated alleles.
Annals of the rheumatic diseases - 1 Aug 2017
Cruz Giovanna Ibeth, Shao Xiaorong, Quach Hong, Ho Kimberly A, Sterba Kirsten, Noble Janelle A, Patsopoulos Nikolaos A, Busch Michael P, Triulzi Darrell J, Wong Wendy Sw, Solomon Benjamin D, Niederhuber John E, Criswell Lindsey A, Barcellos Lisa F
Abstract excerpt
OBJECTIVE: To investigate whether a child's genotype affects a mother's risk of rheumatoid arthritis (RA) beyond the risk associated with her genotype and to test whether exposure to fetal alleles inherited from the father increases risk of RA among mothers without risk alleles. METHODS: A case-control study was conducted among 1165 mothers (170 cases/995 controls) and their respective 1482 children. We tested...
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