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Article

Protective effect of noninherited maternal HLA-DR antigens on rheumatoid arthritis development.

Proceedings of the National Academy of Sciences of the United States of America - 11 Dec 2007

Feitsma Anouk L, Worthington Jane, van der Helm-van Mil Annette H M, Plant Darren, Thomson Wendy, Ursum Jennie, van Schaardenburg Dirkjan, van der Horst-Bruinsma Irene E, van Rood Jon J, Huizinga Tom W J, Toes René E M, de Vries René R P

Abstract excerpt

Rheumatoid arthritis (RA) is a complex genetic disorder in which the HLA-region contributes most to the genetic risk. HLA-DRB1-molecules containing the amino acid sequence DERAA (i.e., HLA-DRB1*0103, *0402, *1102, *1103, *1301, *1302, and *1304) are associated with protection from RA. It has been...

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Identifiers

PMID: 18077428
DOI: 10.1073/pnas.0710260104
PMCID: PMC2148406

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18077428-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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