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Article

Effect of APOL1 disease risk variants on APOL1 gene product.

Bioscience reports - 30 Apr 2017

Haque Shabirul, Patil Gauri, Mishra Abheepsa, Lan Xiqian, Popik Waldemar, Malhotra Ashwani, Skorecki Karl, Singhal Pravin C

Abstract excerpt

Gene sequence mutations may alter mRNA transcription, transcript stability, protein translation, protein stability and protein folding. Apolipoprotein L1 (APOL1) has two sets of sequence variants that are risk factors for kidney disease development, APOL1G1 (substitution mutation) and APOL1G2 (deletion mutation). Our present study focuses on the impact of these variants on APOL1 mRNA transcription and...

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Share to Apolipoprotein L1
Share to Endoplasmic Reticulum Chaperone BiP

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Open in PubMed Open full text

Identifiers

PMID: 28385815
DOI: 10.1042/BSR20160531
PMCID: PMC5408699

Genes

APOL1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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