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Article

The Retromer Supports AMPA Receptor Trafficking During LTP.

Neuron - 5 Apr 2017

Temkin Paul, Morishita Wade, Goswami Debanjan, Arendt Kristin, Chen Lu, Malenka Robert

Abstract excerpt

Alterations in the function of the retromer, a multisubunit protein complex that plays a specialized role in endosomal sorting, have been linked to Alzheimer's and Parkinson's diseases, yet little is known about the retromer's role in the mature brain. Using in vivo knockdown of the critical retromer component VPS35, we demonstrate a specific role for this endosomal sorting complex in the trafficking of AMPA...

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Share to Amyloid beta-Peptides
Share to Amyloid beta-Protein Precursor
Share to Endosomal Sorting Complexes Required for Transport

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Long-Term Potentiation

Share to Receptors, AMPA

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Source

Identifiers

PMID: 28384478
DOI: 10.1016/j.neuron.2017.03.020

Genes

VPS35
APP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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The Retromer Supports AMPA Receptor Trafficking During LTP.PMID 28384478Read ↗

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