Article
No evidence of a role of the β4 subunit of the nicotinic acetylcholine receptor in alcohol-related behaviors.
BMC research notes - 5 Apr 2017
Kamens Helen M, Silva Constanza, McCarthy Riley, Cox Ryan J, Ehringer Marissa A
Abstract excerpt
BACKGROUND: Nicotinic acetylcholine receptors have gained attention in the last several years as mediators of alcohol-related behaviors. The genes that code for the α5, α3, and β4 subunits (Chrna5, Chrna3, and Chrnb4, respectively) map adjacent to each other on human chromosome 15/mouse chromosome 9. Genetic variants in this region have been associated with alcohol phenotypes and mice that overexpress these three...
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