Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Delineation of the role of nicotinic acetylcholine receptor genes in alcohol preference in mice.

Behavior genetics - 1 Sept 2010

Symons Melissa N, Weng Julia, Diehl Eric, Heo Eileen, Kleiber Morgan L, Singh Shiva M

Abstract excerpt

The genetic factors that increase risk for alcohol and nicotine addiction have been elusive, although the frequent co-abuse of these drugs suggests they may act on a common biological pathway. A site of action for both nicotine and alcohol effects in the brain are neuronal nicotinic acetylcholine receptors (nAChR). This report explores the association between six nAChR subunit genes (Chrna3, Chrna4, Chrnb4,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alcohol Drinking
Share to alpha7 Nicotinic Acetylcholine Receptor

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Chromosomes, Mammalian

Share to Crosses, Genetic

Share to Ethanol

Share to Mice, Inbred DBA

Share to Nerve Tissue Proteins

Share to Receptors, Nicotinic

Source

Identifiers

PMID: 20496163
DOI: 10.1007/s10519-010-9366-9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Delineation of the role of nicotinic acetylcholine receptor genes in alcohol preference in mice.PMID 20496163Read ↗

Modulation of Nicotine but Not Ethanol Preference by the Mouse Chrna4 A529T Polymorphism.Semantic proximity Read ↗

Differential contribution of genetic variation in multiple brain nicotinic cholinergic receptors to nicotine dependence: recent progress and emerging open questions.Semantic proximity Read ↗

Genetic variability in nicotinic acetylcholine receptors and nicotine addiction: converging evidence from human and animal research.Semantic proximity Read ↗

Genetic variation within the Chrna7 gene modulates nicotine reward-like phenotypes in mice.Semantic proximity Read ↗

Associations of rare nicotinic cholinergic receptor gene variants to nicotine and alcohol dependence.Semantic proximity Read ↗

The nicotinic acetylcholine receptor CHRNA5/A3/B4 gene cluster: dual role in nicotine addiction and lung cancer.Semantic proximity Read ↗

Overexpression of the CHRNA5/A3/B4 genomic cluster in mice increases the sensitivity to nicotine and modifies its reinforcing effects.Semantic proximity Read ↗

Nicotinic acetylcholine receptors containing α6 subunits contribute to alcohol reward-related behaviours.Semantic proximity Read ↗

Subtypes of nicotinic acetylcholine receptors in nicotine reward, dependence, and withdrawal: evidence from genetically modified mice.Semantic proximity Read ↗

Genetic susceptibility to nicotine addiction: Advances and shortcomings in our understanding of the CHRNA5/A3/B4 gene cluster contribution.Semantic proximity Read ↗

Quantitative Trait Loci Involved in Genetic Predisposition to Acute Alcohol Withdrawal in MiceSemantic proximity Read ↗

Mutation of the α5 nicotinic acetylcholine receptor subunit increases ethanol and nicotine consumption in adolescence and impacts adult drug consumption.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.