Article
Gene variants in responsiveness to clopidogrel have no impact on clinical outcomes in Chinese patients undergoing percutaneous coronary intervention - A multicenter study.
International journal of cardiology - 1 Aug 2017
Li Chenze, Zhang Lina, Wang Haoran, Li Sha, Zhang Yan, You Ling, Sun Yang, Wang Dong, Yang Jun, Cui Yinghua, Cao Yanyan, Shen Xiaoqing, Wang Yan, Cui Wei, Yan Jiangtao, Zeng Hesong, Guo Xiaomei, Li Jianjun, Wang Dao Wen
Abstract excerpt
BACKGROUND: Gene variants contribute to variability in individual responsiveness to clopidogrel and influence cardiovascular outcomes in Caucasian patients with acute coronary syndrome (ACS). However, limited data is available in Asian populations. METHODS: We resequenced 14 genes in metabolizing and activity pathway of clopidogrel in 138 patients with ACS and prospectively assessed the modulating effects of 13...
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