Article
Clopidogrel Pharmacogenetics in Iranian Patients Undergoing Percutaneous Coronary Intervention.
Cardiovascular toxicology - 1 Oct 2018
Mahdieh Nejat, Rabbani Ahmad, Firouzi Ata, Zahedmehr Ali, Hoseinimoghaddam Maryam, Saedi Sedigheh, Sanati Hamidreza, Basiri Hosseinali, Noohi Feridoun, Rabbani Bahareh, Maleki Majid
Abstract excerpt
Clopidogrel is used in patients with coronary syndromes and at risk of thrombotic events or receiving percutaneous coronary intervention (PCI) for reducing heart attack and stroke. Here we present genotype and phenotype study of Iranian patients undergoing PCI treated with clopidogrel during a 6-month period of follow-up; common variants of CYP2C19, CYP3A5, CYP3A4, and ABCB1 genes were determined as well as the...
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