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Article

Clinical, pharmacokinetic, and pharmacogenetic determinants of clopidogrel resistance in Korean patients with acute coronary syndrome.

The Korean journal of laboratory medicine - 1 Apr 2011

Park Kyoung-Jin, Chung Hae-Sun, Kim Suk-Ran, Kim Hee-Jin, Han Ju-Yong, Lee Soo-Youn

Abstract excerpt

BACKGROUND: Clopidogrel has been widely used to prevent recurrent ischemia in patients with acute coronary syndrome (ACS). However, inter-individual variability in response to clopidogrel has been a problem in the clinical setting. The aim of the present study was to investigate the frequency of clopidogrel resistance and to determine the clinical, pharmacokinetic, and pharmacogenetic factors for clopidogrel...

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Acute Coronary Syndrome
Aryl Hydrocarbon Hydroxylases
Clopidogrel
Cytochrome P-450 CYP2C19
Diabetes Complications

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Platelet Aggregation Inhibitors

Republic of Korea

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Identifiers

PMID: 21474982
DOI: 10.3343/kjlm.2011.31.2.91
PMCID: PMC3116006

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