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Article

The Role of Genetic Polymorphism and Other Factors on Clopidogrel Resistance (CR) in an Asian Population with Coronary Heart Disease (CHD).

Molecules (Basel, Switzerland) - 1 Apr 2021

Al-Kaif Mohammed Ahmed, Daud Nur Aizati Athirah, Sha'aban Abubakar, Ng Mei Li, Abdul Kader Muhamad Ali Sk, Noor Dzul Azri Mohamed, Ibrahim Baharudin

Abstract excerpt

Clopidogrel is a widely-used antiplatelet drug. It is important for the treatment and prevention of coronary heart disease. Clopidogrel can effectively reduce platelet activity and therefore reduce stent thrombosis. However, some patients still have ischemic events despite taking the clopidogrel due to the alteration in clopidogrel metabolism attributable to various genetic and non-genetic factors. This review...

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Identifiers

PMID: 33915807
DOI: 10.3390/molecules26071987
PMCID: PMC8036376

Genes

CYP2C19

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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