Article
Two common mutations within CYP2C19 affected platelet aggregation in Chinese patients undergoing PCI: a one-year follow-up study.
The pharmacogenomics journal - 1 Apr 2019
Wang Zhifu, Liu Zhaohui, Wang Wenyao, Fu Yuanyuan, Chen Wen, Li Wenke, Zhang Xue, Tang Yida, Zhou Zhou
Abstract excerpt
The effect of dual antiplatelet therapy, clopidogrel combined with aspirin, was influenced by CYP2C19 gene mutation and heterogeneity of population. Related studies remained controversial and limited, especially in Chinese. Total 3295 unrelated ACS Chinese patients undergoing percutaneous coronary intervention (PCI) were recruited and followed up to 1 year. Meanwhile, baseline and clinical data were retrieved....
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