Article
[Clopidogrel metabolism related gene polymorphisms in Chinese patients with acute coronary syndrome].
Zhonghua xin xue guan bing za zhi - 1 Nov 2012
Feng Guang-xun, Liang Yan, Bai Ying, Chen Tao, Liu Xin, Yang Yan-min, Wang Xing-yu, Yang Yue-jin, Zhu Jun
Abstract excerpt
OBJECTIVE: To detect the single nucleotide polymorphisms of clopidogrel metabolism related genes (CYP2C19, ABCB1 and PON1) in Chinese patients with acute coronary syndrome (ACS) by genotype analysis. METHODS: Genetic analysis was performed in patients admitted to Fuwai Hospital from 2005 to 2008 with ACS within 4 weeks. The detection of polymorphisms was performed by TaqMan real-time PCR method. The alleles...
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