Article
An interaction network of mental disorder proteins in neural stem cells.
Translational psychiatry - 4 Apr 2017
Moen M J, Adams H H H, Brandsma J H, Dekkers D H W, Akinci U, Karkampouna S, Quevedo M, Kockx C E M, Ozgür Z, van IJcken W F J, Demmers J, Poot R A
Abstract excerpt
Mental disorders (MDs) such as intellectual disability (ID), autism spectrum disorders (ASD) and schizophrenia have a strong genetic component. Recently, many gene mutations associated with ID, ASD or schizophrenia have been identified by high-throughput sequencing. A substantial fraction of these mutations are in genes encoding transcriptional regulators. Transcriptional regulators associated with different MDs...
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