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Article

Connecting myelin-related and synaptic dysfunction in schizophrenia with SNP-rich gene expression hubs.

Scientific reports - 6 Apr 2017

Hegyi Hedi

Abstract excerpt

Combining genome-wide mapping of SNP-rich regions in schizophrenics and gene expression data in all brain compartments across the human life span revealed that genes with promoters most frequently mutated in schizophrenia are expression hubs interacting with far more genes than the rest of the genome. We summed up the differentially methylated "expression neighbors" of genes that fall into one of 108 distinct...

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Share to DNA Methylation
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 28382934
DOI: 10.1038/srep45494
PMCID: PMC5382542

Genes

ALDOA
DGCR6
MOBP
RRAS
SYNGR1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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