Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Analysis of Cardiac Myocyte Maturation Using CASAAV, a Platform for Rapid Dissection of Cardiac Myocyte Gene Function In Vivo

30 Mar 2017

Abstract excerpt

RATIONALE: Loss-of-function studies in cardiac myocytes (CMs) are currently limited by the need for appropriate conditional knockout alleles. The factors that regulate CM maturation are poorly understood. Previous studies on CM maturation have been confounded by heart dysfunction caused by whole organ gene inactivation. OBJECTIVE: To develop a new technical platform to rapidly characterize cell-autonomous gene...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cardiac electrophysiology and arrhythmias
Share to Cardiomyopathy and Myosin Studies
Share to Congenital heart defects research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 28356340
DOI: 10.1161/circresaha.116.310283

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Analysis of Cardiac Myocyte Maturation Using CASAAV, a Platform for Rapid Dissection of Cardiac Myocyte Gene Function In VivoPMID 28356340Read ↗

Epigenetic Regulation of Cardiomyocyte Maturation by Arginine Methyltransferase CARM1Semantic proximity Read ↗

Sarcomeres regulate murine cardiomyocyte maturation through MRTF-SRF signaling.Semantic proximity Read ↗

HSBP7 Rescue of a Titin Cardiomyopathy Identified by Morphological ProfilingSemantic proximity Read ↗

Massively parallel in vivo CRISPR screening identifies RNF20/40 as epigenetic regulators of cardiomyocyte maturation.Semantic proximity Read ↗

Transmembrane protein 2 (Tmem2) is required to regionally restrict atrioventricular canal boundary and endocardial cushion development.Semantic proximity Read ↗

Long noncoding RNA <i>VENTHEART</i> is required for cardiomyocyte specification and functionSemantic proximity Read ↗

Cronos Titin Is Expressed in Human Cardiomyocytes and Necessary for Normal Sarcomere FunctionSemantic proximity Read ↗

Maturation of human cardiac organoids enables complex disease modeling and drug discoverySemantic proximity Read ↗

Cardiac Applications of CRISPR/AAV-Mediated Precise Genome EditingSemantic proximity Read ↗

In vivo CRISPR screening identifies RNF20/40 as epigenetic regulators of cardiomyocyte maturationSemantic proximity Read ↗

A transcriptional enhancer regulates cardiac maturation.Semantic proximity Read ↗

Histone demethylase KDM5 regulates cardiomyocyte maturation by promoting fatty acid oxidation, oxidative phosphorylation, and myofibrillar organizationSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.