Article
MicroRNAs Establish Uniform Traits during the Architecture of Vertebrate Embryos.
Developmental cell - 27 Mar 2017
Kasper Dionna M, Moro Albertomaria, Ristori Emma, Narayanan Anand, Hill-Teran Guillermina, Fleming Elizabeth, Moreno-Mateos Miguel, Vejnar Charles E, Zhang Jing, Lee Donghoon, Gu Mengting, Gerstein Mark, Giraldez Antonio, Nicoli Stefania
Abstract excerpt
Proper functioning of an organism requires cells and tissues to behave in uniform, well-organized ways. How this optimum of phenotypes is achieved during the development of vertebrates is unclear. Here, we carried out a multi-faceted and single-cell resolution screen of zebrafish embryonic blood vessels upon mutagenesis of single and multi-gene microRNA (miRNA) families. We found that embryos lacking particular...
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