Article
A new level of complexity: the role of microRNAs in cardiovascular development.
Circulation research - 30 Mar 2012
Boettger Thomas, Braun Thomas
Abstract excerpt
The discovery of the regulatory role of noncoding RNAs, and micro (mi)RNAs in particular, has added a new layer of complexity to our understanding of cardiovascular development. miRNAs regulate and modulate various steps of cardiovascular morphogenesis, cell proliferation, differentiation, and phenotype modulation. miRNAs simultaneously regulate multiple targets, and many miRNAs can bind to the same target,...
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