Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

TERT promoter mutations in telomere biology.

Mutation research. Reviews in mutation research - 1 Jan 2000

Heidenreich Barbara, Kumar Rajiv

Abstract excerpt

Telomere repeats at chromosomal ends, critical to genome integrity, are maintained through an elaborate network of proteins and pathways. Shelterin complex proteins shield telomeres from induction of DNA damage response to overcome end protection problem. A specialized ribonucleic protein, telomerase, maintains telomere homeostasis through repeat addition to counter intrinsic shortcomings of DNA replication that...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Mutation
Share to Promoter Regions, Genetic
Share to Telomerase

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Telomere

Share to TERT gene

Source

Identifiers

PMID: 28342451
DOI: 10.1016/j.mrrev.2016.11.002

Genes

TERT
GABPA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

TERT promoter mutations in telomere biology.PMID 28342451Read ↗

Occurrence, functionality and abundance of the TERT promoter mutations.Semantic proximity Read ↗

Understanding TERT Promoter Mutations: A Common Path to Immortality.Semantic proximity Read ↗

Reactivation of telomerase reverse transcriptase expression in cancer: the role of TERT promoter mutationsSemantic proximity Read ↗

The Solo Play of TERT Promoter Mutations.Semantic proximity Read ↗

Occurrence, functionality, and abundance of the <i>TERT</i> promoter mutationsSemantic proximity Read ↗

Reactivation of telomerase in cancer.Semantic proximity Read ↗

Mechanisms underlying the activation of TERT transcription and telomerase activity in human cancer: old actors and new playersSemantic proximity Read ↗

TERT gene: its function and dysregulation in cancerSemantic proximity Read ↗

TERT—Regulation and Roles in Cancer FormationSemantic proximity Read ↗

Cancer-Specific Telomerase Reverse Transcriptase (TERT) Promoter Mutations: Biological and Clinical ImplicationsSemantic proximity Read ↗

Telomerase Regulation: A Role for EpigeneticsSemantic proximity Read ↗

TERT promoter mutations in cancer development.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.