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Article

Reactivation of telomerase in cancer.

Cellular and molecular life sciences : CMLS - 1 Apr 2016

Akincilar Semih Can, Unal Bilal, Tergaonkar Vinay

Abstract excerpt

Activation of telomerase is a critical step in the development of about 85 % of human cancers. Levels of Tert, which encodes the reverse transcriptase subunit of telomerase, are limiting in normal somatic cells. Tert is subjected to transcriptional, post-transcriptional and epigenetic regulation, but the precise mechanism of how telomerase is re-activated in cancer cells is poorly understood. Reactivation of the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 26846696
DOI: 10.1007/s00018-016-2146-9
PMCID: PMC4805692

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Reactivation of telomerase in cancer.PMID 26846696Read ↗

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