Association of IL-27 rs153109 and rs17855750 Polymorphisms with Risk and Response to Therapy in Acute Lymphoblastic Leukemia.

doi:10.1007/s12253-017-0295-2

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Article

Association of IL-27 rs153109 and rs17855750 Polymorphisms with Risk and Response to Therapy in Acute Lymphoblastic Leukemia.

Pathology oncology research : POR - 1 Jul 2018

Ghavami Alireza, Fathpour Gholamreza, Amirghofran Zahra

Abstract excerpt

Interleukin (IL)-27 is a cytokine with important anti-cancer activity. This study has evaluated the effects of IL-27 rs153109 and rs17855750 single nucleotide polymorphisms (SNPs) on risk of acute lymphoblastic leukemia (ALL) development, as well as their impact on prognosis and patient survival. A total of 200 patients and 210 healthy subjects were genotyped by polymerase chain reaction-restriction fragment...

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PMID: 28828696
DOI: 10.1007/s12253-017-0295-2

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