Article
Plasma levels of apolipoprotein E, APOE genotype and risk of dementia and ischemic heart disease: A review.
Atherosclerosis - 1 Dec 2016
Rasmussen Katrine Laura
Abstract excerpt
Dementia is one of the major causes of disability in later life, and ischemic heart disease is a leading cause of morbidity and mortality. Apolipoprotein E (apoE) plays a pivotal role in lipoprotein metabolism in the brain and in the periphery, and is implicated in both dementia and ischemic heart disease. Peripherally, liver-derived apoE is the main source of plasma apoE. Approximately half of plasma apoE is...
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