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Mechanisms linking apolipoprotein E isoforms with cardiovascular and neurological diseases

5 Jun 2010

Abstract excerpt

PURPOSE OF REVIEW: The purpose of this review is to provide insights into recent advances in mechanisms linking apolipoprotein (apo) E isoforms to cardiovascular and neurological diseases. RECENT FINDINGS: Human apoE has three common isoforms (apoE2, apoE3, and apoE4) with different structural and biophysical properties and different effects on lipid and neuronal homeostasis. ApoE is a protein constituent of...

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PMID: 20531185
DOI: 10.1097/mol.0b013e32833af368

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