Article
An efficient weighted tag SNP-set analytical method in genome-wide association studies.
BMC genetics - 13 Mar 2015
Yan Bin, Wang Shudong, Jia Huaqian, Liu Xing, Wang Xinzeng
Abstract excerpt
BACKGROUND: Single-nucleotide polymorphism (SNP)-set analysis in Genome-wide association studies (GWAS) has emerged as a research hotspot for identifying genetic variants associated with disease susceptibility. But most existing methods of SNP-set analysis are affected by the quality of SNP-set, and poor quality of SNP-set can lead to low power in GWAS. RESULTS: In this research, we propose an efficient weighted...
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