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Article

Partial Reprogramming of Pluripotent Stem Cell-Derived Cardiomyocytes into Neurons.

Scientific reports - 22 Mar 2017

Chuang Wenpo, Sharma Arun, Shukla Praveen, Li Guang, Mall Moritz, Rajarajan Kuppusamy, Abilez Oscar J, Hamaguchi Ryoko, Wu Joseph C, Wernig Marius, Wu Sean M

Abstract excerpt

Direct reprogramming of somatic cells has been demonstrated, however, it is unknown whether electrophysiologically-active somatic cells derived from separate germ layers can be interconverted. We demonstrate that partial direct reprogramming of mesoderm-derived cardiomyocytes into neurons is feasible, generating cells exhibiting structural and electrophysiological properties of both cardiomyocytes and neurons....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 28327614
DOI: 10.1038/srep44840
PMCID: PMC5361100

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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