Article
Generation of Functional Murine Cardiac Myocytes From Induced Pluripotent Stem Cells
15 Jul 2008
Abstract excerpt
BACKGROUND: The recent breakthrough in the generation of induced pluripotent stem (iPS) cells, which are almost indistinguishable from embryonic stem (ES) cells, facilitates the generation of murine disease- and human patient-specific stem cell lines. The aim of this study was to characterize the cardiac differentiation potential of a murine iPS cell clone in comparison to a well-established murine ES cell line....
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